METABOLIN-1 combines the clinically studied and branded ingredients Pomolive (R) and BERGAVIT that could be a useful treatment to decrease fat deposits in overweight and obese individuals, reduce waist circumference, an important predictive cardiovascular risk marker, lower basal glycemia, protecting against insulin resistance, lower elevated triglycerides that herald the onset of atherosclerosis and can benefit cardiovascular health by, improving the HDL/LDL ratio. Vitamin B6, vitamin B12 and folate are the cofactors and methyl donors needed to promote methylation and convert homocysteine into useful amino acids.