Joint Health Supports Healthy Joint Function Plus Chondroitin Sulfate Non-GMO A Dietary Supplement General Health Family Owned Since 1968 GMP Quality Assured NOW Glucosamine & MSM with Chondroitin Sulfate combines three well-known joint support ingredients. Glucosamine is an essential building block for the formation of glycosaminoglycans (GAGs) and proteoglycans, the main components of cartilage tissue. These compounds promote water retention within the joint, giving resiliency by acting as a lubricant and a means to absorb shock. MSM (Methylsulfonylmethane) is an organic form of sulfur, a mineral necessary for the production of GAGs and proteoglycans. NOW Foods developed the glucosamine test method chosen as the official AOACI industry standard method.